# Protective Effect of Tranexamic Acid on Shedding of the Endothelial Glycocalyx in Patients Undergoing Spinal Fusion Surgery

> **NCT03697681** · NA · COMPLETED · sponsor: **Yonsei University** · enrollment: 128 (actual)

## Conditions studied

- Posterior Lumbar Spinal Fusion Surgery

## Interventions

- **DRUG:** Tranexamic acid
- **DRUG:** 0.9% NaCl (normal saline)

## Key facts

- **NCT ID:** NCT03697681
- **Lead sponsor:** Yonsei University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-10-16
- **Primary completion:** 2020-08-12
- **Final completion:** 2020-08-12
- **Target enrollment:** 128 (ACTUAL)
- **Last updated:** 2020-10-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03697681

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03697681, "Protective Effect of Tranexamic Acid on Shedding of the Endothelial Glycocalyx in Patients Undergoing Spinal Fusion Surgery". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT03697681. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*