# FIRE AND ICE II Trial Pilot

> **NCT03706677** · NA · COMPLETED · sponsor: **Medtronic Cardiac Rhythm and Heart Failure** · enrollment: 69 (actual)

## Conditions studied

- Persistent Atrial Fibrillation
- Atrial Arrhythmia

## Interventions

- **DEVICE:** Cryoballoon (Arctic Front Advance Cryoballoon)
- **DEVICE:** Radiofrequency Catheter (ThermoCool Smarttouch)

## Key facts

- **NCT ID:** NCT03706677
- **Lead sponsor:** Medtronic Cardiac Rhythm and Heart Failure
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-04-05
- **Primary completion:** 2023-04-06
- **Final completion:** 2023-04-06
- **Target enrollment:** 69 (ACTUAL)
- **Last updated:** 2023-11-29

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03706677

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03706677, "FIRE AND ICE II Trial Pilot". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT03706677. Licensed CC0.

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