# Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BIA 5-1058

> **NCT03708146** · PHASE1 · COMPLETED · sponsor: **Bial - Portela C S.A.** · enrollment: 157 (actual)

## Conditions studied

- Cardiovascular Disease+Pulmonary Disease
- Pulmonary Arterial Hypertension

## Interventions

- **DRUG:** BIA 5-1058
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT03708146
- **Lead sponsor:** Bial - Portela C S.A.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-05-28
- **Primary completion:** 2019-03-18
- **Final completion:** 2019-03-18
- **Target enrollment:** 157 (ACTUAL)
- **Last updated:** 2020-12-31


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03708146

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03708146, "Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BIA 5-1058". Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/clinical/NCT03708146. Licensed CC0.

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