# Non-invasive Vagus Nerve Stimulation for the Prevention of Migraines

> **NCT03716505** · NA · COMPLETED · sponsor: **ElectroCore INC** · enrollment: 231 (actual)

## Conditions studied

- Migraine Disorders

## Interventions

- **DEVICE:** gammaCore Sapphire active
- **DEVICE:** gammaCore Sapphire Sham

## Key facts

- **NCT ID:** NCT03716505
- **Lead sponsor:** ElectroCore INC
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-11-02
- **Primary completion:** 2020-09-09
- **Final completion:** 2020-09-09
- **Target enrollment:** 231 (ACTUAL)
- **Last updated:** 2020-09-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03716505

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03716505, "Non-invasive Vagus Nerve Stimulation for the Prevention of Migraines". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT03716505. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
