# Combination HTNV and PUUV DNA Vaccine

> **NCT03718130** · PHASE1 · COMPLETED · sponsor: **U.S. Army Medical Research and Development Command** · enrollment: 61 (actual)

## Conditions studied

- Hantaan Virus Disease, Puumala Virus

## Interventions

- **COMBINATION_PRODUCT:** Hantaan virus vaccine (HTNV) - Using TriGrid Delivery System (TDS) for Intradermal Delivery (ID)
- **COMBINATION_PRODUCT:** Hantaan virus vaccine (HTNV) - Using TriGrid Delivery System (TDS) for Intramuscular Delivery (IM)
- **COMBINATION_PRODUCT:** Puumala virus vaccine (PUUV) - Using the TriGrid Delivery System (TDS) for Intradermal Delivery (ID)
- **COMBINATION_PRODUCT:** Puumala virus vaccine (PUUV) - Using the TriGrid Delivery System (TDS) for Intramuscular Delivery (IM)
- **COMBINATION_PRODUCT:** Hantaan/Puumala (HTNV/PUUV) virus vaccines - Using the TriGrid Delivery System (TDS) for Intradermal Delivery (ID)
- **COMBINATION_PRODUCT:** Hantaan/Puumala (HTNV/PUUV virus vaccines - Using the TriGrid Delivery System (TDS) for Intramusular Delivery (IM)

## Key facts

- **NCT ID:** NCT03718130
- **Lead sponsor:** U.S. Army Medical Research and Development Command
- **Sponsor class:** FED
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-07-10
- **Primary completion:** 2022-10-07
- **Final completion:** 2022-10-07
- **Target enrollment:** 61 (ACTUAL)
- **Last updated:** 2025-06-26

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03718130

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03718130, "Combination HTNV and PUUV DNA Vaccine". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT03718130. Licensed CC0.

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