# Continuation of The Kronos Early Estrogen Prevention Study (KEEPS)

> **NCT03718494** · — · COMPLETED · sponsor: **Mayo Clinic** · enrollment: 299 (actual)

## Conditions studied

- Alzheimer Dementia

## Interventions

- **DIAGNOSTIC_TEST:** Brain Magnetic Resonance Imaging (MRI)
- **DIAGNOSTIC_TEST:** F-18 Florbetapir Positron Emission Tomography (PET) Imaging
- **DIAGNOSTIC_TEST:** F-18 AV-1451 Positron Emission Tomography (PET) Imaging
- **OTHER:** Neuropsychological Testing

## Key facts

- **NCT ID:** NCT03718494
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2019-05-22
- **Primary completion:** 2022-09-01
- **Final completion:** 2022-09-01
- **Target enrollment:** 299 (ACTUAL)
- **Last updated:** 2023-07-17

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03718494

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03718494, "Continuation of The Kronos Early Estrogen Prevention Study (KEEPS)". Retrieved via AI Analytics 2026-07-07 from https://api.ai-analytics.org/clinical/NCT03718494. Licensed CC0.

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