# Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)

> **NCT03726268** · PHASE4 · COMPLETED · sponsor: **Duke University** · enrollment: 907 (actual)

## Conditions studied

- Opioid Use
- Pain, Postoperative

## Interventions

- **DRUG:** Methadone
- **DRUG:** Fentanyl
- **DRUG:** Hydromorphone
- **DRUG:** Morphine
- **DRUG:** Sufentanil

## Key facts

- **NCT ID:** NCT03726268
- **Lead sponsor:** Duke University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-11-29
- **Primary completion:** 2023-07-30
- **Final completion:** 2024-01-30
- **Target enrollment:** 907 (ACTUAL)
- **Last updated:** 2025-11-19

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03726268

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03726268, "Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT03726268. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*