# STep-up and Step-down Therapeutic Strategies in Childhood ARthritiS

> **NCT03728478** · PHASE3 · RECRUITING · sponsor: **Istituto Giannina Gaslini** · enrollment: 260 (estimated)

## Conditions studied

- Oligoarthritis, Juvenile
- Polyarthritis, Juvenile, Rheumatoid Factor Negative

## Interventions

- **DRUG:** Etanercept
- **DRUG:** Methotrexate
- **DRUG:** Intra-articular corticosteroid injections

## Key facts

- **NCT ID:** NCT03728478
- **Lead sponsor:** Istituto Giannina Gaslini
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2019-05-29
- **Primary completion:** 2025-02-28
- **Final completion:** 2025-02-28
- **Target enrollment:** 260 (ESTIMATED)
- **Last updated:** 2024-10-15

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03728478

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03728478, "STep-up and Step-down Therapeutic Strategies in Childhood ARthritiS". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT03728478. Licensed CC0.

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