# Systemic Probiotics in the Periodontal Treatment

> **NCT03733379** · PHASE3 · UNKNOWN · sponsor: **Belén Retamal-Valdes** · enrollment: 176 (estimated)

## Conditions studied

- Periodontitis

## Interventions

- **PROCEDURE:** Scaling and root planing
- **DRUG:** Metronidazole and Amoxicillin placebos
- **DRUG:** Metronidazole
- **DRUG:** Amoxicillin
- **DIETARY_SUPPLEMENT:** Probiotic
- **DIETARY_SUPPLEMENT:** Probiotic placebo

## Key facts

- **NCT ID:** NCT03733379
- **Lead sponsor:** Belén Retamal-Valdes
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2018-11-05
- **Primary completion:** 2020-12-30
- **Final completion:** 2021-12-30
- **Target enrollment:** 176 (ESTIMATED)
- **Last updated:** 2020-01-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03733379

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03733379, "Systemic Probiotics in the Periodontal Treatment". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT03733379. Licensed CC0.

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