Dose-finding Study of SPK-8016 Gene Therapy in Patients With Hemophilia A to Support Evaluation in Individuals With FVIII Inhibitors

Conditions

• Adeno-Associated Virus (AAV)
• Blood Coagulation Disorder
• Blood Coagulation Disorders, Inherited
• Coagulation Protein Disorders
• Factor VIII (FVIII)
• Factor VIII (FVIII) Deficiency
• Factor VIII (FVIII) Gene
• Factor VIII (FVIII) Protein
• Genetic Diseases, Inborn
• Genetic Diseases, X-Linked
• Gene Therapy
• Gene Transfer
• Hematologic Diseases
• Hemorrhagic Disorders
• Recombinant
• Vector
• Inhibitors

Interventions

• GENETIC: SPK-8016

Sponsor

Spark Therapeutics, Inc.