# High-Frequency Oscillation Ventilation Versus Conventional Mechanical Ventilation in Very Preterm Infants With Perinatal Acute Respiratory Distress Syndrome: Multicenters Randomized Controlled, Superiority Trial

> **NCT03736707** · NA · RECRUITING · sponsor: **Daping Hospital and the Research Institute of Surgery of the Third Military Medical University** · enrollment: 400 (estimated)

## Conditions studied

- Acute Respiratory Distress Syndrome
- High Frequency Oscillatory Ventilation
- Preterm
- Conventional Mechanical Ventilation

## Interventions

- **DEVICE:** HFOV
- **DEVICE:** CMV

## Key facts

- **NCT ID:** NCT03736707
- **Lead sponsor:** Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2025-10-01
- **Primary completion:** 2028-06-30
- **Final completion:** 2028-12-31
- **Target enrollment:** 400 (ESTIMATED)
- **Last updated:** 2025-10-06

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03736707

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03736707, "High-Frequency Oscillation Ventilation Versus Conventional Mechanical Ventilation in Very Preterm Infants With Perinatal Acute Respiratory Distress Syndrome: Multicenters Randomized Controlled, Superiority Trial". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT03736707. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*