# The Role of Estrogen in the Neurobiology of Eating Disorders

> **NCT03740204** · PHASE2 · RECRUITING · sponsor: **Massachusetts General Hospital** · enrollment: 120 (estimated)

## Conditions studied

- Eating Disorders
- Hypoestrogenemia

## Interventions

- **DRUG:** 17-β estradiol transdermal patches with cyclic progesterone
- **DRUG:** Placebo patch and pill

## Key facts

- **NCT ID:** NCT03740204
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2019-06-13
- **Primary completion:** 2026-09-30
- **Final completion:** 2026-12-31
- **Target enrollment:** 120 (ESTIMATED)
- **Last updated:** 2025-05-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03740204

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03740204, "The Role of Estrogen in the Neurobiology of Eating Disorders". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT03740204. Licensed CC0.

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