# Diuretic Effect of Metolazone Pre-dosing Versus Concurrent Dosing

> **NCT03746002** · PHASE4 · TERMINATED · sponsor: **University of Maryland, Baltimore** · enrollment: 3 (actual)

## Conditions studied

- Fluid Overload
- Heart Failure Acute

## Interventions

- **DRUG:** Metolazone 60 minutes prior to furosemide
- **DRUG:** Metolazone concurrently with furosemide

## Key facts

- **NCT ID:** NCT03746002
- **Lead sponsor:** University of Maryland, Baltimore
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2019-01-01
- **Primary completion:** 2020-01-10
- **Final completion:** 2020-01-10
- **Target enrollment:** 3 (ACTUAL)
- **Why stopped:** Insufficient rate of patient enrollment/accrual.
- **Last updated:** 2021-10-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03746002

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03746002, "Diuretic Effect of Metolazone Pre-dosing Versus Concurrent Dosing". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT03746002. Licensed CC0.

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