Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer

NCT03775265 · clinicaltrials.gov ↗

PHASE3

Phase

ACTIVE_NOT_RECRUITING

Status

475

Enrollment

NIH

Sponsor class

Conditions

Bladder Urothelial Carcinoma
Muscle Invasive Bladder Carcinoma
Stage II Bladder Cancer AJCC v8
Stage IIIA Bladder Cancer AJCC v8

Interventions

DRUG: Atezolizumab
PROCEDURE: Biopsy of Bladder
DRUG: Cisplatin
PROCEDURE: Computed Tomography
PROCEDURE: Cystoscopy
DRUG: Fluorouracil
DRUG: Gemcitabine
PROCEDURE: Magnetic Resonance Imaging
DRUG: Mitomycin
OTHER: Quality-of-Life Assessment
RADIATION: Radiation Therapy
OTHER: Survey Administration
PROCEDURE: Transurethral Resection of Bladder Tumor

Sponsor

National Cancer Institute (NCI)