# Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension

> **NCT03787082** · PHASE1 · WITHDRAWN · sponsor: **Gladwin, Mark, MD**

## Conditions studied

- Pulmonary Hypertension
- Heart Failure With Normal Ejection Fraction
- Pulmonary Heart Disease and Diseases of Pulmonary Circulation

## Interventions

- **DRUG:** Nitrates
- **DRUG:** Chlorhexidine Gluconate Mouthwash
- **DRUG:** Placebo Mouthwash

## Key facts

- **NCT ID:** NCT03787082
- **Lead sponsor:** Gladwin, Mark, MD
- **Sponsor class:** INDIV
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2022-12
- **Primary completion:** 2023-12
- **Final completion:** 2023-12
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Study was never able to start after the pandemic restrictions lifted
- **Last updated:** 2022-07-07

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03787082

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03787082, "Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension". Retrieved via AI Analytics 2026-07-08 from https://api.ai-analytics.org/clinical/NCT03787082. Licensed CC0.

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