# A Study to Evaluate Central Nervous System (CNS) Pharmacodynamic Activity of TAK-653 in Healthy Participants Using Transcranial Magnetic Stimulation (TMS)

> **NCT03792672** · PHASE1 · COMPLETED · sponsor: **Neurocrine Biosciences** · enrollment: 24 (actual)

## Conditions studied

- Healthy Volunteers

## Interventions

- **DRUG:** TAK-653
- **DRUG:** Placebo
- **DRUG:** Ketamine

## Key facts

- **NCT ID:** NCT03792672
- **Lead sponsor:** Neurocrine Biosciences
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-02-11
- **Primary completion:** 2019-05-15
- **Final completion:** 2019-06-18
- **Target enrollment:** 24 (ACTUAL)
- **Last updated:** 2021-03-19

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03792672

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03792672, "A Study to Evaluate Central Nervous System (CNS) Pharmacodynamic Activity of TAK-653 in Healthy Participants Using Transcranial Magnetic Stimulation (TMS)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT03792672. Licensed CC0.

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