# Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases

> **NCT03796273** · EARLY_PHASE1 · TERMINATED · sponsor: **Wake Forest University Health Sciences** · enrollment: 15 (actual)

## Conditions studied

- Anatomic Stage IV Breast Cancer AJCC v8
- Astrocytoma
- Breast Carcinoma Metastatic in the Brain
- Glioma
- Invasive Breast Carcinoma
- Oligodendroglioma
- Prognostic Stage IV Breast Cancer AJCC v8
- Recurrent Glioma

## Interventions

- **OTHER:** Best Practice
- **DRUG:** Ketoconazole

## Key facts

- **NCT ID:** NCT03796273
- **Lead sponsor:** Wake Forest University Health Sciences
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2019-03-13
- **Primary completion:** 2022-10-23
- **Final completion:** 2022-10-23
- **Target enrollment:** 15 (ACTUAL)
- **Why stopped:** Low accruals
- **Last updated:** 2026-03-20

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03796273

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03796273, "Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases". Retrieved via AI Analytics 2026-07-07 from https://api.ai-analytics.org/clinical/NCT03796273. Licensed CC0.

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