# Stimulant Therapy Targeted to Individualized Connectivity Maps to Promote ReACTivation of Consciousness

> **NCT03814356** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **Massachusetts General Hospital** · enrollment: 10 (actual)

## Conditions studied

- Brain Injury Traumatic Severe (Diagnosis)
- Coma
- Consciousness, Level Altered
- Anoxic Brain Injury

## Interventions

- **DRUG:** Methylphenidate

## Key facts

- **NCT ID:** NCT03814356
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2020-08-24
- **Primary completion:** 2024-04-01
- **Final completion:** 2026-06-30
- **Target enrollment:** 10 (ACTUAL)
- **Last updated:** 2025-10-29

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03814356

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03814356, "Stimulant Therapy Targeted to Individualized Connectivity Maps to Promote ReACTivation of Consciousness". Retrieved via AI Analytics 2026-07-06 from https://api.ai-analytics.org/clinical/NCT03814356. Licensed CC0.

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