# Mode of Action of Ondansetron, a 5-HT Receptor 3 Antagonist, in Lactulose Induced Diarrhoea

> **NCT03833999** · PHASE4 · COMPLETED · sponsor: **University of Nottingham** · enrollment: 16 (actual)

## Conditions studied

- Motility Disorder of Intestine
- Ondansetron
- Small Bowel Water

## Interventions

- **DRUG:** Ondansetron 8mg
- **DIAGNOSTIC_TEST:** abdominal MRI
- **DRUG:** Lactulose
- **DRUG:** Placebo oral capsule

## Key facts

- **NCT ID:** NCT03833999
- **Lead sponsor:** University of Nottingham
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-10-16
- **Primary completion:** 2019-06-27
- **Final completion:** 2019-06-27
- **Target enrollment:** 16 (ACTUAL)
- **Last updated:** 2019-11-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03833999

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03833999, "Mode of Action of Ondansetron, a 5-HT Receptor 3 Antagonist, in Lactulose Induced Diarrhoea". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT03833999. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
