# A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection

> **NCT03834740** · EARLY_PHASE1 · COMPLETED · sponsor: **St. Joseph's Hospital and Medical Center, Phoenix** · enrollment: 27 (actual)

## Conditions studied

- Glioblastoma Multiforme
- Glioma of Brain

## Interventions

- **DRUG:** Ribociclib
- **DRUG:** Everolimus

## Key facts

- **NCT ID:** NCT03834740
- **Lead sponsor:** St. Joseph's Hospital and Medical Center, Phoenix
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-01-19
- **Primary completion:** 2022-02-18
- **Final completion:** 2022-02-18
- **Target enrollment:** 27 (ACTUAL)
- **Last updated:** 2025-05-30

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03834740

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03834740, "A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection". Retrieved via AI Analytics 2026-06-27 from https://api.ai-analytics.org/clinical/NCT03834740. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*