# ENAC Blockade and Arterial Stiffness

> **NCT03837626** · PHASE2,PHASE3 · COMPLETED · sponsor: **University of Missouri-Columbia** · enrollment: 137 (actual)

## Conditions studied

- Overweight and Obesity
- Insulin Resistance

## Interventions

- **DRUG:** Placebo - Cap
- **DRUG:** Amiloride Pill

## Key facts

- **NCT ID:** NCT03837626
- **Lead sponsor:** University of Missouri-Columbia
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-07-15
- **Primary completion:** 2024-10-05
- **Final completion:** 2025-04-30
- **Target enrollment:** 137 (ACTUAL)
- **Last updated:** 2025-12-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03837626

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03837626, "ENAC Blockade and Arterial Stiffness". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT03837626. Licensed CC0.

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