# Trial Comparing a Multi-Modal Pain Protocol With and Without Opioids Following Total Joint Arthroplasty

> **NCT03845881** · EARLY_PHASE1 · COMPLETED · sponsor: **Mayo Clinic** · enrollment: 45 (actual)

## Conditions studied

- Total Knee Arthroplasty

## Interventions

- **DRUG:** Oxycodone
- **DRUG:** Placebo Oral Tablet

## Key facts

- **NCT ID:** NCT03845881
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-04-10
- **Primary completion:** 2020-07-28
- **Final completion:** 2020-07-28
- **Target enrollment:** 45 (ACTUAL)
- **Last updated:** 2020-07-30

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03845881

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03845881, "Trial Comparing a Multi-Modal Pain Protocol With and Without Opioids Following Total Joint Arthroplasty". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT03845881. Licensed CC0.

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