# High Versus Low Bicarbonate Bath in Critically-ill Patients Receiving Continuous Renal Replacement Therapy

> **NCT03846258** · PHASE4 · WITHDRAWN · sponsor: **Mayo Clinic**

## Conditions studied

- Metabolic Acidosis
- Acute Kidney Injury
- Acute Kidney Failure

## Interventions

- **DRUG:** Low bicarbonate solution (22 mmol/L)
- **DRUG:** High Bicarbonate solution (32 mmol/L)

## Key facts

- **NCT ID:** NCT03846258
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2019-05-01
- **Primary completion:** 2024-04-01
- **Final completion:** 2024-04-01
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Due to the fact that we were unable to find subjects who met all inclusion and exclusion criteria it was determined to withdraw this study.
- **Last updated:** 2021-04-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03846258

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03846258, "High Versus Low Bicarbonate Bath in Critically-ill Patients Receiving Continuous Renal Replacement Therapy". Retrieved via AI Analytics 2026-07-07 from https://api.ai-analytics.org/clinical/NCT03846258. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
