# Single Versus Multi-Dose Oral and Intravenous Tranexamic Acid Patients at High Risk for Blood Transfusion After Spine Surgery

> **NCT03849443** · EARLY_PHASE1 · RECRUITING · sponsor: **Rush University Medical Center** · enrollment: 604 (estimated)

## Conditions studied

- Open Posterior Thoracolumbar Spinal Fusion Procedure

## Interventions

- **DRUG:** Tranexamic Acid Injectable Product (1000 mg intravenous bolus)
- **DRUG:** Vitamin C 250 MG Oral Tablet
- **DRUG:** Tranexamic Acid 650Mg Tablet

## Key facts

- **NCT ID:** NCT03849443
- **Lead sponsor:** Rush University Medical Center
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2019-08-26
- **Primary completion:** 2026-12-01
- **Final completion:** 2027-01-01
- **Target enrollment:** 604 (ESTIMATED)
- **Last updated:** 2026-01-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03849443

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03849443, "Single Versus Multi-Dose Oral and Intravenous Tranexamic Acid Patients at High Risk for Blood Transfusion After Spine Surgery". Retrieved via AI Analytics 2026-07-13 from https://api.ai-analytics.org/clinical/NCT03849443. Licensed CC0.

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