# Individualized Hemodynamic Optimization by Indirect Measurement of the Respiratory Quotient in Major Surgery: Prospective Randomized Multicentre Open-Label Study (OPHIQUE) Individualized Optimization by Indirect Measurement of the Respiratory Quotient

> **NCT03852147** · NA · COMPLETED · sponsor: **Centre Hospitalier Universitaire, Amiens** · enrollment: 350 (actual)

## Conditions studied

- Post-Op Complication
- Respiratory Complication

## Interventions

- **PROCEDURE:** : hemodynamic management

## Key facts

- **NCT ID:** NCT03852147
- **Lead sponsor:** Centre Hospitalier Universitaire, Amiens
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-12-26
- **Primary completion:** 2022-12-26
- **Final completion:** 2023-01-26
- **Target enrollment:** 350 (ACTUAL)
- **Last updated:** 2025-09-22

## Collaborators

- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03852147

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03852147, "Individualized Hemodynamic Optimization by Indirect Measurement of the Respiratory Quotient in Major Surgery: Prospective Randomized Multicentre Open-Label Study (OPHIQUE) Individualized Optimization by Indirect Measurement of the Respiratory Quotient". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT03852147. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*