# Kinetics of Elimination of Methotrexate and Its Major Metabolite 7-OH-methotrexate for Observant Patients

> **NCT03852888** · NA · COMPLETED · sponsor: **CHU de Reims** · enrollment: 62 (actual)

## Conditions studied

- Rheumatoid Arthritis

## Interventions

- **BIOLOGICAL:** Urine samples taken to measure methotrexate and its major metabolite 7-OH-methotrexate level

## Key facts

- **NCT ID:** NCT03852888
- **Lead sponsor:** CHU de Reims
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-11-14
- **Primary completion:** 2020-11-23
- **Final completion:** 2021-11-25
- **Target enrollment:** 62 (ACTUAL)
- **Last updated:** 2026-01-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03852888

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03852888, "Kinetics of Elimination of Methotrexate and Its Major Metabolite 7-OH-methotrexate for Observant Patients". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT03852888. Licensed CC0.

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