# Study of Rapastinel as Monotherapy in Major Depressive Disorder (MDD)

> **NCT03855865** · PHASE3 · WITHDRAWN · sponsor: **Naurex, Inc, an affiliate of Allergan plc**

## Conditions studied

- Depressive Disorder, Major

## Interventions

- **DRUG:** Rapastinel
- **DRUG:** Vortioxetine
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT03855865
- **Lead sponsor:** Naurex, Inc, an affiliate of Allergan plc
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2019-07-01
- **Primary completion:** 2020-12-31
- **Final completion:** 2020-12-31
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Business decision to stop the program.
- **Last updated:** 2019-07-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03855865

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03855865, "Study of Rapastinel as Monotherapy in Major Depressive Disorder (MDD)". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT03855865. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*