# Corneal Collagen Cross-Linking (CXL) Performed With "Epi-ON" Versus "Epi-OFF" in Eyes With Keratoconus and Other Corneal Ectatic Disorders

> **NCT03858036** · PHASE3 · UNKNOWN · sponsor: **Center for Sight, Sacramento, CA** · enrollment: 550 (estimated)

## Conditions studied

- Keratoconus
- Ectasia

## Interventions

- **DRUG:** Ricrolin+
- **DEVICE:** VEGA UV-A system

## Key facts

- **NCT ID:** NCT03858036
- **Lead sponsor:** Center for Sight, Sacramento, CA
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2019-03-08
- **Primary completion:** 2024-12-31
- **Final completion:** 2024-12-31
- **Target enrollment:** 550 (ESTIMATED)
- **Last updated:** 2019-02-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03858036

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03858036, "Corneal Collagen Cross-Linking (CXL) Performed With "Epi-ON" Versus "Epi-OFF" in Eyes With Keratoconus and Other Corneal Ectatic Disorders". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT03858036. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*