# Pessary Versus Cerclage With or Without Progesterone in Twins

> **NCT03863613** · NA · TERMINATED · sponsor: **Mỹ Đức Hospital** · enrollment: 219 (actual)

## Conditions studied

- Preterm Birth
- Twin Pregnancy
- Short Cervix

## Interventions

- **DEVICE:** Pessary
- **PROCEDURE:** Cervical cerclage
- **DRUG:** Vaginal progesterone

## Key facts

- **NCT ID:** NCT03863613
- **Lead sponsor:** Mỹ Đức Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2019-03-23
- **Primary completion:** 2023-07-08
- **Final completion:** 2023-07-29
- **Target enrollment:** 219 (ACTUAL)
- **Why stopped:** Due to safety concerns as the PTB \<28 weeks and perinatal death rates were significantly higher in the pessary group, following the DSMC's recommendation.
- **Last updated:** 2024-02-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03863613

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03863613, "Pessary Versus Cerclage With or Without Progesterone in Twins". Retrieved via AI Analytics 2026-07-02 from https://api.ai-analytics.org/clinical/NCT03863613. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*