# Identifying Best Approach in Improving Quality of Life and Survival After a Donor Stem Cell Transplant in Older, Medically Infirm, or Frail Patients With Blood Diseases

> **NCT03870750** · PHASE2,PHASE3 · TERMINATED · sponsor: **Fred Hutchinson Cancer Center** · enrollment: 458 (actual)

## Conditions studied

- Hematopoietic and Lymphoid Cell Neoplasm
- Non-Neoplastic Hematologic and Lymphocytic Disorder

## Interventions

- **OTHER:** Supportive Palliative Care
- **OTHER:** Clinical Management
- **OTHER:** Best Practice
- **PROCEDURE:** Allogeneic Hematopoietic Stem Cell Transplantation
- **OTHER:** Questionnaire Administration
- **OTHER:** Quality-of-Life Assessment
- **OTHER:** Survey Administration

## Key facts

- **NCT ID:** NCT03870750
- **Lead sponsor:** Fred Hutchinson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2019-08-15
- **Primary completion:** 2025-12-31
- **Final completion:** 2025-12-31
- **Target enrollment:** 458 (ACTUAL)
- **Why stopped:** Study terminated due to meeting interim analysis futility endpoint. No difference was found between two treatment arms at interim analysis of primary outcome.
- **Last updated:** 2026-01-12

## Collaborators

- National Cancer Institute (NCI)
- National Institutes of Health (NIH)

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03870750

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03870750, "Identifying Best Approach in Improving Quality of Life and Survival After a Donor Stem Cell Transplant in Older, Medically Infirm, or Frail Patients With Blood Diseases". Retrieved via AI Analytics 2026-08-21 from https://api.ai-analytics.org/clinical/NCT03870750. Licensed CC0.

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