# Azithromycin-Prevention in Labor Use Study (A-PLUS)

> **NCT03871491** · PHASE3 · COMPLETED · sponsor: **NICHD Global Network for Women's and Children's Health** · enrollment: 58747 (actual)

## Conditions studied

- Maternal Death
- Maternal Infections Affecting Fetus or Newborn
- Neonatal SEPSIS
- Maternal Sepsis During Labor
- Neonatal Death
- Postpartum Sepsis

## Interventions

- **DRUG:** Azithromycin
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT03871491
- **Lead sponsor:** NICHD Global Network for Women's and Children's Health
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-09-01
- **Primary completion:** 2022-09-30
- **Final completion:** 2022-09-30
- **Target enrollment:** 58747 (ACTUAL)
- **Last updated:** 2024-10-24

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03871491

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03871491, "Azithromycin-Prevention in Labor Use Study (A-PLUS)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT03871491. Licensed CC0.

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