# β-blockers Withdrawal in Patients With HFpEF and Chronotropic Incompetence: Effect on Functional Capacity (Preserve-HR)

> **NCT03871803** · PHASE4 · COMPLETED · sponsor: **Fundación para la Investigación del Hospital Clínico de Valencia** · enrollment: 52 (actual)

## Conditions studied

- Heart Failure With Normal Ejection Fraction
- Chronotropic Incompetence

## Interventions

- **DRUG:** Controlled withdrawal of beta-blockers
- **DIAGNOSTIC_TEST:** Cardiopulmonary Exercise Testing

## Key facts

- **NCT ID:** NCT03871803
- **Lead sponsor:** Fundación para la Investigación del Hospital Clínico de Valencia
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-10-01
- **Primary completion:** 2021-02-27
- **Final completion:** 2021-02-27
- **Target enrollment:** 52 (ACTUAL)
- **Last updated:** 2021-03-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03871803

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03871803, "β-blockers Withdrawal in Patients With HFpEF and Chronotropic Incompetence: Effect on Functional Capacity (Preserve-HR)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT03871803. Licensed CC0.

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