# Non Inferiority Study of Preoperative Chemotherapy Without Pelvic Irradiation for Rectal Cancer

> **NCT03875781** · PHASE3 · RECRUITING · sponsor: **Assistance Publique - Hôpitaux de Paris** · enrollment: 540 (estimated)

## Conditions studied

- Rectal Cancer
- Advanced Cancer

## Interventions

- **DRUG:** Chemotherapy
- **DRUG:** Radiochemotherapy

## Key facts

- **NCT ID:** NCT03875781
- **Lead sponsor:** Assistance Publique - Hôpitaux de Paris
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2019-06-05
- **Primary completion:** 2026-12-05
- **Final completion:** 2026-12-05
- **Target enrollment:** 540 (ESTIMATED)
- **Last updated:** 2026-01-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03875781

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03875781, "Non Inferiority Study of Preoperative Chemotherapy Without Pelvic Irradiation for Rectal Cancer". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT03875781. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*