Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors

NCT03878095 · clinicaltrials.gov ↗

PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

24

Enrollment

NIH

Sponsor class

Conditions

Malignant Solid Neoplasm
Refractory Cholangiocarcinoma
Refractory Malignant Solid Neoplasm

Interventions

PROCEDURE: Biopsy Procedure
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
DRUG: Ceralasertib
PROCEDURE: Computed Tomography
PROCEDURE: Magnetic Resonance Imaging
DRUG: Olaparib

Sponsor

National Cancer Institute (NCI)