# Bioavailability Mechanistic Study of Hot-Melt Extruded Amorphous Solid Dispersions

> **NCT03886766** · NA · COMPLETED · sponsor: **University Hospital, Basel, Switzerland** · enrollment: 16 (actual)

## Conditions studied

- Biological Availability
- Amorphous Solid Dispersions

## Interventions

- **DRUG:** Hot-melt extruded amorphous solid dispersion of Efavirenz
- **DRUG:** Hot-melt extruded amorphous solid dispersion of Efavirenz homogenized to drug rich particles
- **DRUG:** Efavirenz solution

## Key facts

- **NCT ID:** NCT03886766
- **Lead sponsor:** University Hospital, Basel, Switzerland
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-04-30
- **Primary completion:** 2020-03-19
- **Final completion:** 2020-03-19
- **Target enrollment:** 16 (ACTUAL)
- **Last updated:** 2024-12-20

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03886766

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03886766, "Bioavailability Mechanistic Study of Hot-Melt Extruded Amorphous Solid Dispersions". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT03886766. Licensed CC0.

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