# Plasmapheresis Versus Plasma Infusion from Young APOE3 Homozygotes Into MCI APOE4 Homozygotes to Slow Disease Progression

> **NCT03887741** · PHASE1 · COMPLETED · sponsor: **Mayo Clinic** · enrollment: 3 (actual)

## Conditions studied

- Mild Cognitive Impairment

## Interventions

- **BIOLOGICAL:** Plasmapheresis
- **BIOLOGICAL:** Plasma infusion

## Key facts

- **NCT ID:** NCT03887741
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-09-15
- **Primary completion:** 2024-02-16
- **Final completion:** 2024-02-16
- **Target enrollment:** 3 (ACTUAL)
- **Last updated:** 2024-12-31


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03887741

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03887741, "Plasmapheresis Versus Plasma Infusion from Young APOE3 Homozygotes Into MCI APOE4 Homozygotes to Slow Disease Progression". Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/clinical/NCT03887741. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*