# Imaging mGluR5 and Synaptic Density in Psychiatric Disorders

> **NCT03898297** · — · ACTIVE_NOT_RECRUITING · sponsor: **Yale University** · enrollment: 120 (estimated)

## Conditions studied

- Major Depressive Disorder
- Bipolar Disorder
- Healthy

## Interventions

- **RADIATION:** [18F]FPEB
- **RADIATION:** [11C]APP311

## Key facts

- **NCT ID:** NCT03898297
- **Lead sponsor:** Yale University
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2017-01-11
- **Primary completion:** 2026-04
- **Final completion:** 2026-04
- **Target enrollment:** 120 (ESTIMATED)
- **Last updated:** 2025-06-24

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03898297

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03898297, "Imaging mGluR5 and Synaptic Density in Psychiatric Disorders". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT03898297. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*