# Collagenase Clostridium Histolyticum for Refractory Iatrogenic Esophageal Strictures

> **NCT03898661** · EARLY_PHASE1 · TERMINATED · sponsor: **University Hospital, Ghent** · enrollment: 2 (actual)

## Conditions studied

- Stricture
- Esophageal Stricture
- Anastomotic
- Collagenosis

## Interventions

- **DRUG:** Collagenase histiolyticum

## Key facts

- **NCT ID:** NCT03898661
- **Lead sponsor:** University Hospital, Ghent
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2019-03-29
- **Primary completion:** 2020-06-30
- **Final completion:** 2021-01-01
- **Target enrollment:** 2 (ACTUAL)
- **Why stopped:** unexpected serious adverse event
- **Last updated:** 2023-09-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03898661

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03898661, "Collagenase Clostridium Histolyticum for Refractory Iatrogenic Esophageal Strictures". Retrieved via AI Analytics 2026-07-19 from https://api.ai-analytics.org/clinical/NCT03898661. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*