# Novel PET Radioligand as an Inflammatory Biomarker in Musculoskeletal Conditions

> **NCT03912428** · PHASE1 · TERMINATED · sponsor: **National Institute of Mental Health (NIMH)** · enrollment: 31 (actual)

## Conditions studied

- Myositis
- Inflammatory
- Rheumatoid Arthritis
- Healthy Volunteers

## Interventions

- **DRUG:** 11C-MC1
- **DRUG:** Celecoxib
- **DRUG:** [11C]ER176
- **DIAGNOSTIC_TEST:** Positron Emission Tomography (PET)/computed tomography (CT) Scan

## Key facts

- **NCT ID:** NCT03912428
- **Lead sponsor:** National Institute of Mental Health (NIMH)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2019-06-14
- **Primary completion:** 2024-06-14
- **Final completion:** 2024-06-14
- **Target enrollment:** 31 (ACTUAL)
- **Why stopped:** due to difficulty with participant recruitment and data futility
- **Last updated:** 2025-09-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03912428

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03912428, "Novel PET Radioligand as an Inflammatory Biomarker in Musculoskeletal Conditions". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT03912428. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*