# Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Colorectal Carcinoma. CHECK Study.

> **NCT03914820** · NA · UNKNOWN · sponsor: **Mario Negri Institute for Pharmacological Research** · enrollment: 330 (estimated)

## Conditions studied

- Colorectal Neoplasms

## Interventions

- **PROCEDURE:** HIPEC CO2 surgery
- **PROCEDURE:** Standard surgery
- **DRUG:** Mitomycin

## Key facts

- **NCT ID:** NCT03914820
- **Lead sponsor:** Mario Negri Institute for Pharmacological Research
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2020-06-19
- **Primary completion:** 2025-06-01
- **Final completion:** 2025-06-01
- **Target enrollment:** 330 (ESTIMATED)
- **Last updated:** 2023-10-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03914820

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03914820, "Prophylactic Surgery Plus HIPEC With CO2 in Patients Affected by Colorectal Carcinoma. CHECK Study.". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT03914820. Licensed CC0.

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