# The Effects of Gut Micribiota Disruption on the Immune Response After Open Heart Surgery

> **NCT03939273** · NA · UNKNOWN · sponsor: **Radboud University Medical Center** · enrollment: 80 (estimated)

## Conditions studied

- Systemic Inflammatory Response Syndrome
- Postoperative Shock
- Coronary Artery Disease
- Extracorporeal Circulation; Complications

## Interventions

- **DRUG:** Vancomycin Oral
- **DRUG:** Metronidazole Oral
- **DRUG:** Ciprofloxacin Pill
- **DRUG:** Fluconazole Oral Product
- **DRUG:** Placebos

## Key facts

- **NCT ID:** NCT03939273
- **Lead sponsor:** Radboud University Medical Center
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2022-03
- **Primary completion:** 2023-03
- **Final completion:** 2023-03
- **Target enrollment:** 80 (ESTIMATED)
- **Last updated:** 2021-03-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03939273

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03939273, "The Effects of Gut Micribiota Disruption on the Immune Response After Open Heart Surgery". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT03939273. Licensed CC0.

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