# The Role of Neuroactive Steroids in Stress, Drug Craving and Drug Use in Cocaine Use Disorders

> **NCT03953612** · EARLY_PHASE1 · COMPLETED · sponsor: **Yale University** · enrollment: 58 (actual)

## Conditions studied

- Cocaine-Related Disorders

## Interventions

- **DRUG:** Pregnenolone (PREG)
- **DRUG:** Placebos

## Key facts

- **NCT ID:** NCT03953612
- **Lead sponsor:** Yale University
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-03-12
- **Primary completion:** 2023-05-08
- **Final completion:** 2023-05-08
- **Target enrollment:** 58 (ACTUAL)
- **Last updated:** 2024-07-03

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03953612

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03953612, "The Role of Neuroactive Steroids in Stress, Drug Craving and Drug Use in Cocaine Use Disorders". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT03953612. Licensed CC0.

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