# Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging

> **NCT03954899** · NA · RECRUITING · sponsor: **Natalie Denburg** · enrollment: 230 (estimated)

## Conditions studied

- Mild Cognitive Impairment
- Cognitive Decline
- Healthy Aging

## Interventions

- **DIETARY_SUPPLEMENT:** melatonin
- **OTHER:** placebo

## Key facts

- **NCT ID:** NCT03954899
- **Lead sponsor:** Natalie Denburg
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2019-11-12
- **Primary completion:** 2025-11
- **Final completion:** 2025-11
- **Target enrollment:** 230 (ESTIMATED)
- **Last updated:** 2025-03-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03954899

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03954899, "Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT03954899. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*