# PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) Radioligand

> **NCT03958630** · PHASE1 · TERMINATED · sponsor: **National Institute of Mental Health (NIMH)** · enrollment: 13 (actual)

## Conditions studied

- Dementia

## Interventions

- **DRUG:** 11C-ER176
- **DRUG:** 11C-PIB
- **DIAGNOSTIC_TEST:** Positron Emission Tomography (PET) Scan

## Key facts

- **NCT ID:** NCT03958630
- **Lead sponsor:** National Institute of Mental Health (NIMH)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2019-07-03
- **Primary completion:** 2021-05-27
- **Final completion:** 2023-12-04
- **Target enrollment:** 13 (ACTUAL)
- **Why stopped:** PI closed the protocol due to low recruitment
- **Last updated:** 2024-05-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03958630

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03958630, "PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) Radioligand". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT03958630. Licensed CC0.

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