TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801)

Conditions

• Acute Leukemia
• Chronic Myelogenous Leukemia (CML)
• Myelodysplasia
• Lymphoma

Interventions

• PROCEDURE: Mobilized Peripheral Blood Stem Cell graft with Tacrolimus/Methotrexate
• DRUG: Tacrolimus
• DRUG: Methotrexate
• PROCEDURE: Mobilized Peripheral Blood Stem Cell graft with Tacrolimus/Mycophenolate Mofetil/Post-Transplant Cyclophosphamide
• DRUG: Tacrolimus
• DRUG: Mycophenolate Mofetil
• DRUG: Cyclophosphamide

Sponsor

Medical College of Wisconsin

Collaborators

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