# Effect of Multiple Doses of Modafinil on the Pharmacokinetics of Single Dose Lorlatinib in Healthy Participants

> **NCT03961997** · PHASE1 · COMPLETED · sponsor: **Pfizer** · enrollment: 16 (actual)

## Conditions studied

- Adult
- Drug Interactions
- Healthy Volunteers
- Humans

## Interventions

- **DRUG:** Lorlatinib 50 mg
- **DRUG:** Lorlatinib 75 mg
- **DRUG:** Lorlatinib 100 mg

## Key facts

- **NCT ID:** NCT03961997
- **Lead sponsor:** Pfizer
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-08-22
- **Primary completion:** 2019-12-09
- **Final completion:** 2019-12-09
- **Target enrollment:** 16 (ACTUAL)
- **Last updated:** 2020-01-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03961997

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03961997, "Effect of Multiple Doses of Modafinil on the Pharmacokinetics of Single Dose Lorlatinib in Healthy Participants". Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/clinical/NCT03961997. Licensed CC0.

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