Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy

NCT03965689 · clinicaltrials.gov ↗

PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

27

Enrollment

NIH

Sponsor class

Conditions

Metastatic Lung Non-Small Cell Squamous Carcinoma
Metastatic Lung Non-Squamous Non-Small Cell Carcinoma
Stage IIIB Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8
Stage IVA Lung Cancer AJCC v8
Stage IVB Lung Cancer AJCC v8
Unresectable Lung Non-Small Cell Carcinoma
Unresectable Lung Non-Squamous Non-Small Cell Carcinoma

Interventions

DRUG: Carboplatin
DRUG: Paclitaxel
DRUG: Pevonedistat

Sponsor

National Cancer Institute (NCI)