# Randomized, Open Label Safety Trial of Dapivirine Vaginal Ring and Oral TRUVADA® Use in Pregnancy

> **NCT03965923** · PHASE3 · COMPLETED · sponsor: **National Institute of Allergy and Infectious Diseases (NIAID)** · enrollment: 1104 (actual)

## Conditions studied

- HIV Infections

## Interventions

- **DRUG:** Dapivirine (DPV) Vaginal Ring (VR)
- **DRUG:** Truvada Tablet

## Key facts

- **NCT ID:** NCT03965923
- **Lead sponsor:** National Institute of Allergy and Infectious Diseases (NIAID)
- **Sponsor class:** NIH
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-01-09
- **Primary completion:** 2024-05-13
- **Final completion:** 2024-05-13
- **Target enrollment:** 1104 (ACTUAL)
- **Last updated:** 2025-08-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03965923

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03965923, "Randomized, Open Label Safety Trial of Dapivirine Vaginal Ring and Oral TRUVADA® Use in Pregnancy". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT03965923. Licensed CC0.

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