# Determination of the Dissociation Constant (Ka) of Plasma and Whole Blood in Septic Patients

> **NCT03966664** · — · UNKNOWN · sponsor: **Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico** · enrollment: 90 (estimated)

## Conditions studied

- Sepsis
- Septic Shock
- Critical Illness
- Respiratory Acidosis
- Respiratory Alkalosis
- Acid-Base Imbalance

## Interventions

- **DIAGNOSTIC_TEST:** In vitro determination the dissociation constant (Ka) and total amount of non-volatile buffers (Atot) in isolated plasma.
- **DIAGNOSTIC_TEST:** In vitro determination the dissociation constant (Ka) and total amount of non-volatile buffers (Atot) in whole blood
- **DIAGNOSTIC_TEST:** Biomolecular analysis of plasma proteins.

## Key facts

- **NCT ID:** NCT03966664
- **Lead sponsor:** Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** UNKNOWN
- **Start date:** 2019-06-03
- **Primary completion:** 2021-06
- **Final completion:** 2021-06
- **Target enrollment:** 90 (ESTIMATED)
- **Last updated:** 2019-06-04

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03966664

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03966664, "Determination of the Dissociation Constant (Ka) of Plasma and Whole Blood in Septic Patients". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT03966664. Licensed CC0.

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