# Triplet Combination or Doublet Regimen Versus Chemoradiation as Neoadjuvant Therapy for Locally Advanced Rectal Cancer

> **NCT03975049** · PHASE3 · NOT_YET_RECRUITING · sponsor: **Sixth Affiliated Hospital, Sun Yat-sen University** · enrollment: 933 (estimated)

## Conditions studied

- Rectal Cancer
- Chemotherapy Effect

## Interventions

- **RADIATION:** Chemoradiation
- **DRUG:** FOLFOXIRI Protocol
- **DRUG:** Folfox Protocol

## Key facts

- **NCT ID:** NCT03975049
- **Lead sponsor:** Sixth Affiliated Hospital, Sun Yat-sen University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2019-08
- **Primary completion:** 2024-07
- **Final completion:** 2029-07
- **Target enrollment:** 933 (ESTIMATED)
- **Last updated:** 2019-06-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03975049

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03975049, "Triplet Combination or Doublet Regimen Versus Chemoradiation as Neoadjuvant Therapy for Locally Advanced Rectal Cancer". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT03975049. Licensed CC0.

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